The state Department of Technology, Management & Budget announced the November job figure Wednesday, saying the drop followed three months when the jobless rate remained steady at 9 percent.
Nationally, the seasonally adjusted unemployment rate fell 0.3 in November to 7 percent.
The state said Michigan's jobless rate remains unchanged from November 2012.
The state's seasonally adjusted civilian workforce fell by 17,000 in the latest month to 4.707 million. The state agency said the number of people working also fell by 7,000 to 4.294 million.
Total employment in Michigan is up by 69,000 since November 2012.