Adam Coates, 30, and his brother, Andrew Coates, 26, were pronounced dead at the scene, Kempker said.
The two men were back-seat passengers in a car driven by Dustin Whorley, 27, also of Lowell.
Whorley was traveling north on 168th Avenue and failed to stop for a stop sign at Riley, Kempker said. Whorley’s 1992 Plymouth Duster proceeded into the intersection where it was hit by an eastbound Plymouth Neon driven by Kimberly Ledesma, 18 of Holland.
The Coates brothers were not wearing seatbelts and were ejected from the car on impact, Kempker said.
Whorley suffered minor injuries and was taken to Holland Hospital. The front seat passenger in Whorley’s car, Blake Simon, 22, of Grand Haven, was not injured.
Ledesma and her two passengers, Sara Ledesma, 20, and Erika Morales, 20, both of Holland, were all taken to Holland Hospital where they were treated and released.
The accident is still under investigation.