The crash happened at about 2:45 p.m. at the intersection of Whitbeck and Fruitvale roads in Montague Township.
According to Muskegon County deputies, the man's car flipped twice after the collision and ended up in a nearby field.
The driver, a man in his 20s, was killed instantly in the crash, police said. A passenger in his car suffered injuries and was taken to a Muskegon County hospital for evaluation.
The driver of the minivan was not injured.
Deputies did not immediately release the names of the people involved in the crash.