A 15-year-old girl disappeared around 7:30 p.m. Friday near the south breakwall at Pere Marquette Beach.
A witness said a woman on a raft swam out and tried to rescue two distressed swimmers but was only able to reach one.
Initial scanner traffic indicated four people were in the water, but the Coast Guard said at this time they are only searching for one individual.
The rip current along lake Michigan is extremely strong. Earlier Friday, the Coast Guard warned swimmers to stay out of Lake Michigan because of three to six foot waves and dangerous rip currents.