A 23-year-old Kentwood man was taken by ambulance to North Ottawa Community Hospital following the 9:36 p.m. crash, said Sgt. Greg Rotman of the Ottawa County Sheriff's Department. He was in stable condition.
Christopher Hodge, 24, of Zeeland, was taken by ambulance to Butterworth Hospital in Grand Rapids. He was in serious condition, police said.
The crash occurred when the Kentwood man, whom police declined to name, failed to stop at a stop sign at Lake Michigan Drive. He was traveling north on 120th at the time in his 2003 Audi.
His vehicle struck a 2001 Ford Focus, which Hodge was driving east on Lake Michigan Drive.
Police said alcohol was a factor in the crash.
The crash is still under investigation.