The crash occurred at 9:04 p.m. on 48th Avenue, north of Lake Michigan Drive, in Allendale Township.
Police said Gregory L. Pierson was not wearing a helmet at the time of the crash.
Sgt. Cal Keuning of the Ottawa County Sheriff’s Office said Pierson was driving his motorcycle south on 48th Avenue when he was struck by a car turning off 48th onto University Park.
The car was driven by Lynsey Raschke, 22, of Highland. Raschke suffered minor injuries.
GVSU police were nearby and administered CPR to the motorcyclist upon arrival, Keuning said. However, Pierson was pronounced dead at the scene.
The incident remains under investigation.